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A genome-wide association study on amyotrophic lateral sclerosis in the Taiwanese Han population.

Biomarkers in medicine - 1 Jun 2016

Chen Chi-Jim, Chen Chien-Ming, Pai Tun-Wen, Chang Hao-Teng, Hwang Chi-Shin

Abstract excerpt

Identification of mutations in patients with amyotrophic lateral sclerosis (ALS) in a genome-wide association study can reveal possible biomarkers of such a rapidly progressive and fatal neurodegenerative disease. It was observed that significant single nucleotide polymorphisms vary when the tested population changes from one ethnic group to another. To identify new loci associated with ALS susceptibility in the...

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PMID: 26580837
DOI: 10.2217/bmm.15.115

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