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Global proteome of <em>LonP1</em><sup>+/-</sup> mouse embryonal fibroblasts reveals impact on respiratory chain, but no interdependence between Eral1 and mitoribosomes

2019-07-10

Abstract excerpt

Research on healthy ageing shows that lifespan reductions are often caused by mitochondrial dysfunction. Thus, it is very interesting that the deletion of mitochondrial matrix peptidase LonP1 was observed to abolish embryogenesis, while deletion of the mitochondrial matrix peptidase ClpP prolonged survival. To unveil the targets of each enzyme, we documented the global proteome of LonP1+/- mouse embryonal fibrobla...

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Literature Corpus work
23e0a8fb-cee6-5616-8651-b6a3db973608
DOI
10.20944/preprints201907.0144.v1
Open publication

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Global proteome of <em>LonP1</em><sup>+/-</sup> mouse embryonal fibroblasts reveals impact on respiratory chain, but no interdependence between Eral1 and mitoribosomesDOI 10.20944/preprints201907.0144.v1
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