Article
Dilated cardiomyopathy: the complexity of a diverse genetic architecture.
Nature reviews. Cardiology - 1 Sept 2013
Hershberger Ray E, Hedges Dale J, Morales Ana
Abstract excerpt
Remarkable progress has been made in understanding the genetic basis of dilated cardiomyopathy (DCM). Rare variants in >30 genes, some also involved in other cardiomyopathies, muscular dystrophy, or syndromic disease, perturb a diverse set of important myocardial proteins to produce a final DCM phenotype. Large, publicly available datasets have provided the opportunity to evaluate previously identified...
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