Article

Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice

2023-06-23

Abstract excerpt

<h4> Abstract </h4> Spermatogonial stem cells (SSCs) are essential for continuous spermatogenesis and male fertility. The underlying mechanisms of alternative splicing (AS) in mouse SSCs are still largely unclear. We demonstrated that SRSF1 is essential for gene expression and splicing in mouse SSCs. Crosslinking immunoprecipitation and sequencing (CLIP-seq) data revealed that spermatogonia-related genes (e.g.,...

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Literature Corpus work: 23532cce-ff58-5469-ba88-5f28a98919a0
DOI: 10.1101/2023.06.21.545885

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