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Article

The Hippo pathway regulates density-dependent proliferation of iPSC-derived cardiac myocytes

2021-04-12

Abstract excerpt

<h4>ABSTRACT</h4> Inducing cardiac myocytes to proliferate is considered a potential therapy to target heart disease, however, modulating cardiac myocyte proliferation has proven to be a technical challenge. The Hippo pathway is a kinase signaling cascade that regulates cell proliferation during the growth of the heart. Inhibition of the Hippo pathway increases the activation of the transcription factors YAP/TAZ,...

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Literature Corpus work
2318cfc8-e0c5-576e-b98e-b0b9d93aac11
DOI
10.1101/2021.04.12.439529
Open publication

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The Hippo pathway regulates density-dependent proliferation of iPSC-derived cardiac myocytesDOI 10.1101/2021.04.12.439529
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