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Article

Effects of increasing intranuclear calcium levels via MCU inhibition on iPSC-derived cardiomyocyte differentiation and maturation

2025-05-15

Abstract excerpt

<title>Abstract</title> <p>ABSTRCT Background: Cardiovascular diseases remain the leading cause of death worldwide, and the limited efficiency of human-induced pluripotent stem cell-derived cardiomyocyte (hiPSC-CM) differentiation hampers its potential in disease modeling and regenerative therapy. Calcium signaling plays a central role in cardiac maturation, and proper regulation of intracellular calcium dynamics...

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Literature Corpus work
22ec439c-a677-5f33-a291-db661c00afe3
DOI
10.21203/rs.3.rs-6392558/v1
Open publication

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Effects of increasing intranuclear calcium levels via MCU inhibition on iPSC-derived cardiomyocyte differentiation and maturationDOI 10.21203/rs.3.rs-6392558/v1
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