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Article

DNA Repair Pathways in Trypanosomatids: from DNA Repair to Drug Resistance

1 Mar 2014

Abstract excerpt

All living organisms are continuously faced with endogenous or exogenous stress conditions affecting genome stability. DNA repair pathways act as a defense mechanism, which is essential to maintain DNA integrity. There is much to learn about the regulation and functions of these mechanisms, not only in human cells but also equally in divergent organisms. In trypanosomatids, DNA repair pathways protect the genome...

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PMID: 24600040
DOI: 10.1128/mmbr.00045-13

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