Article
DNA repair helicases: from mechanistic understanding to therapeutic implications.
NAR cancer - 1 Dec 2025
Menon Vijay, Gueble Susan E
Abstract excerpt
The maintenance of genomic integrity is paramount for normal cell physiology and survival as well as avoidance of carcinogenesis. Cellular DNA is periodically subjected to a myriad of exogenous and endogenous threats and requires constant monitoring to limit genomic instability. To this end, cells possess an intricate DNA damage response and repair (DDR) module comprised of different classes of protein players....
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