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Article

A practical view of fine-mapping and gene prioritization in the post-genome-wide association era.

Open biology - 1 Jan 2020

Broekema R V, Bakker O B, Jonkers I H

Abstract excerpt

Over the past 15 years, genome-wide association studies (GWASs) have enabled the systematic identification of genetic loci associated with traits and diseases. However, due to resolution issues and methodological limitations, the true causal variants and genes associated with traits remain difficult to identify. In this post-GWAS era, many biological and computational fine-mapping approaches now aim to solve...

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Share to Multifactorial Inheritance
Share to Chromosome Mapping
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Genetics, Population

Share to Quantitative Trait, Heritable

Share to Quantitative Trait Loci

Source

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Identifiers

PMID: 31937202
DOI: 10.1098/rsob.190221
PMCID: PMC7014684

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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