Article

Quinolinate Promotes Immune Tolerance through Macrophage Polarization in Glioblastoma

2022-07-13

Abstract excerpt

<h4>ABSTRACT</h4> There has been considerable scientific effort dedicated to understanding the biologic consequence and therapeutic implications of aberrant tryptophan metabolism in brain tumors and neurodegenerative diseases. An overwhelming majority of this work has focused on the upstream metabolism of tryptophan; however, this has not resulted in clinical application. Using global metabolomic profiling of pat...

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Literature Corpus work: 22482686-835d-5563-bd99-cf359cf7566f
DOI: 10.1101/2022.07.12.499609

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