Article
From the sideline: Tissue-specific nucleoporin function in health and disease, an update.
FEBS letters - 1 Nov 2023
Jühlen Ramona, Fahrenkrog Birthe
Abstract excerpt
The subcellular compartmentalisation of eukaryotic cells requires selective exchange between the cytoplasm and the nucleus. Intact nucleocytoplasmic transport is vital for normal cell function and mutations in the executing machinery have been causally linked to human disease. Central players in nucleocytoplasmic exchange are nuclear pore complexes (NPCs), which are built from ~30 distinct proteins collectively...
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