Article

Deciphering the Diversity of Bacterial Transporters that Salvage Queuosine Precursors

2024-03-05

Abstract excerpt

Queuosine (Q) is a modification of the wobble base of tRNA harboring GUN antico-dons with roles in decoding accuracy and efficiency. Its synthesis is complex with mul-tiple enzymatic steps and several pathway intermediates can be salvaged. The only two transporter families known to salvage Q precursors are QPTR/COG1738 and QrtT/QueT. Analysis of the distribution of known Q synthesis and salvage genes in human gut...

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Literature Corpus work: 21be79c4-1bc3-5d90-b49a-d442b41f5534
DOI: 10.20944/preprints202403.0245.v1

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