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Article

Queuosine modification of tRNA: its divergent role in cellular machinery

23 Nov 2009

Abstract excerpt

tRNAs possess a high content of modified nucleosides, which display an incredible structural variety. These modified nucleosides are conserved in their sequence and have important roles in tRNA functions. Most often, hypermodified nucleosides are found in the wobble position of tRNAs, which play a direct role in maintaining translational efficiency and fidelity, codon recognition, etc. One of such hypermodified...

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PMID: 19925456
DOI: 10.1042/bsr20090057

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