Carbapenem-resistance oprD mutations reshape Pseudomonas aeruginosa host-pathogen interactions during infection.

Abstract excerpt

Antibiotic resistance is a major global health threat. While its role in reducing drug susceptibility is well established, the broader consequences of resistance mutations on bacterial physiology and phenotype during infection remain poorly understood. Carbapenem-resistant Pseudomonas aeruginosa is considered among the highest-priority bacterial threats, with resistance commonly driven by loss-of-function...

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