Article

Prevalence and impact of <i>oprD</i> mutations in <i>Pseudomonas aeruginosa</i> strains in cystic fibrosis

2019-12-09

Abstract excerpt

<h4>ABSTRACT</h4> Defective OprD porins contribute to carbapenem resistance and may be important in Pseudomonas aeruginosa adaptation to cystic fibrosis airways. It is unclear whether oprD mutations are fixed in populations of shared strains that are transmitted between patients or whether novel variants arise during infection. We investigated oprD sequences and antimicrobial resistance of two common Australian sh...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cbcc28a1-89cb-582d-b2fd-7d95edd3007e
DOI: 10.1101/19013870

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Prevalence and impact of <i>oprD</i> mutations in <i>Pseudomonas aeruginosa</i> strains in cystic fibrosisDOI 10.1101/19013870Read

Emergence and impact of oprD mutations in Pseudomonas aeruginosa strains in cystic fibrosis.Semantic proximity Read

Carbapenem-resistance <i>oprD</i> mutations reshape <i>Pseudomonas aeruginosa</i> host-pathogen interactions during infectionSemantic proximity Read

A large-scale comparison shows that genetic changes causing antibiotic resistance in experimentally evolved <i>Pseudomonas aeruginosa</i> predict those in naturally evolved bacteriaSemantic proximity Read

Emergence of a <i>Pseudomonas aeruginosa</i> Hypermutator Strain During the Course of Ventilator-Associated PneumoniaSemantic proximity Read

<i>Achromobacter</i> genetic adaptation in cystic fibrosisSemantic proximity Read

Global genomic diversity of <i>Pseudomonas aeruginosa</i> in bronchiectasisSemantic proximity Read

Divergent <i>In vitro</i> MIC Characteristics and underlying isogenic mutations in host-specialized <i>Pseudomonas aeruginosa</i>Semantic proximity Read

Diversification of Pseudomonas aeruginosa within the cystic fibrosis lung and its effects on antibiotic resistanceSemantic proximity Read

Mutation-driven evolution of <i>Pseudomonas aeruginosa</i> in the presence of either ceftazidime or ceftazidime/avibactamSemantic proximity Read

Whole genome sequencing reveals the emergence of a <i>Pseudomonas aeruginosa</i> shared strain sub-lineage among patients treated within a single cystic fibrosis centreSemantic proximity Read

Canonical pathoadaptive cystic fibrosis genes in <i>Pseudomonas aeruginosa</i> are not CF-specificSemantic proximity Read

A Robust Genome-Wide Association Study Uncovers Signature Genetic Alterations among <i>Pseudomonas aeruginosa</i> Cystic Fibrosis IsolatesSemantic proximity Read