Article

H3K27me3 mediated KRT14 upregulation promotes TNBC peritoneal metastasis

2021-02-02

Abstract excerpt

Triple Negative Breast Cancer (TNBC) is known to have poor prognosis and adverse clinical outcome among all breast cancer subtypes due to the absence of available targeted therapy for it. Emerging literature indicates that epigenetic reprogramming is now appreciated as a driving force for TNBC pathophysiology. High expression of epigenetic modulator EZH2 (Enhancer of zeste homolog 2) has been shown to correlate wi...

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Literature Corpus work: 21ace00c-7477-5ebc-ba61-62534c825f54
DOI: 10.1101/2021.02.02.429349

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