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PBP4 is required for serum-induced cell wall thickening and antibiotic tolerance in <i>Staphylococcus aureus</i>

2024-06-19

Abstract excerpt

The bacterial pathogen Staphylococcus aureus responds to the host environment by synthesising a thick peptidoglycan cell wall which protects the bacterium from membrane-targeting antimicrobials and the immune response. However, the proteins required for this response were previously unknown. Here, we demonstrate by three independent approaches that the penicillin binding protein PBP4 is crucial for serum-induced...

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Literature Corpus work
218938e6-bf88-5179-9974-a8af01d7f9b1
DOI
10.1101/2024.06.19.599726
Open publication

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PBP4 is required for serum-induced cell wall thickening and antibiotic tolerance in <i>Staphylococcus aureus</i>DOI 10.1101/2024.06.19.599726
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