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Preclinical evaluation of the efficacy of α−Difluoromethylornithine and Sulindac against SARS-CoV-2 infection

2025-02-28

Abstract excerpt

<h4>ABSTRACT</h4> Despite numerous research efforts and several effective vaccines and therapies developed against COronaVIrus Disease 2019 (COVID-19), drug repurposing remains an attractive alternative to identify new treatments for SARS-CoV-2 virus variants and other viral infections that may emerge in the future. Cellular polyamines support viral propagation and tumor growth. Here we tested the antiviral activ...

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Literature Corpus work
2157ea91-83f9-5f89-87c9-4b0b1f646f9c
DOI
10.1101/2025.02.26.640194
Open publication

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Preclinical evaluation of the efficacy of α−Difluoromethylornithine and Sulindac against SARS-CoV-2 infectionDOI 10.1101/2025.02.26.640194
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