Article

Clofoctol inhibits SARS-CoV-2 replication and reduces lung pathology in mice

2021-06-30

Abstract excerpt

Drug repurposing has the advantage of shortening regulatory preclinical development steps. Here, we screened a library of drug compounds, already registered in one or several geographical areas, to identify those exhibiting antiviral activity against SARS-CoV-2 with relevant potency. Of the 1,942 compounds tested, 21 exhibited a substantial antiviral activity in Vero-81 cells. Among them, clofoctol, an antibacteri...

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Literature Corpus work: 8a54c394-a76f-51fd-a685-9ed2d35ab5a5
DOI: 10.1101/2021.06.30.450483

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