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Mitoquinone mesylate targets SARS-CoV-2 infection in preclinical models

2022-02-25

Abstract excerpt

<h4>Summary</h4> To date, there is no effective oral antiviral against SARS-CoV-2 that is also anti-inflammatory. Herein, we show that the mitochondrial antioxidant mitoquinone/mitoquinol mesylate (Mito-MES), a dietary supplement, has potent antiviral activity against SARS-CoV-2 and its variants of concern in vitro and in vivo . Mito-MES had nanomolar in vitro antiviral potency against the Beta and Delta SARS-...

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Literature Corpus work
7b9fcfb2-53f2-52c2-bd1d-3aa5d320a980
DOI
10.1101/2022.02.22.481100
Open publication

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Mitoquinone mesylate targets SARS-CoV-2 infection in preclinical modelsDOI 10.1101/2022.02.22.481100
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