Article

Utility of family history in disease prediction in the era of polygenic scores

2021-06-28

Abstract excerpt

Clinicians have historically used family history and other risk prediction algorithms to guide patient care and preventive treatment such as statin therapeutics for coronary artery disease. As polygenic scores move towards clinical use, we have begun to consider the interplay of these scores with other predictors for optimal second generation risk prediction. Here, we assess the use of family history and polygenic...

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Literature Corpus work: 214f7b6c-bcc8-5f22-a630-e494a4286fba
DOI: 10.1101/2021.06.25.21259158

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