Article

Bhlhe40 limits proliferation and prevents excessive angiogenesis in mouse embryoid bodies under hypoxia

2024-06-03

Abstract excerpt

Knowledge of the molecular mechanisms that underlie the regulation of the major adaptive responses to an unbalanced oxygen tension is central to understanding tissue homeostasis and disease. Hypoxia-inducible transcription factors (HIFs) coordinate changes in the transcriptome that control these adaptive responses. Here, we focused on the functional role of the transcriptional repressor basic-helix-loop-helix fami...

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Literature Corpus work: 2134c66c-a618-5d78-8925-9aa98d02fe43
DOI: 10.1101/2024.06.03.597199

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