Article

Host immune responses after suprachoroidal delivery of AAV8 in nonhuman primate eyes

2020-09-25

Abstract excerpt

The suprachoroid is a potential space located between the sclera and choroid of the eye which provides a novel route for ocular drug or viral vector delivery. Suprachoroidal injection of AAV8 using transscleral microneedles enables widespread transgene expression in eyes of nonhuman primates, but may cause intraocular inflammation. We characterized the host humoral and cellular immune responses after suprachoroida...

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Identifiers and source

Literature Corpus work: 212091ab-7da5-545b-b212-ebc746fe659d
DOI: 10.1101/2020.09.25.313676

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