Article

Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2

2020-07-09

Abstract excerpt

<h4>SUMMARY</h4> During virus infection B cells are critical for the production of antibodies and protective immunity. Here we show that the human B cell compartment in patients with diagnostically confirmed SARS-CoV-2 and clinical COVID-19 is rapidly altered with the early recruitment of B cells expressing a limited subset of IGHV genes, progressing to a highly polyclonal response of B cells with broader IGHV ge...

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Literature Corpus work: a253b611-daf9-55ee-8b9b-495c27c45450
DOI: 10.1101/2020.07.08.194456

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