Article

scRNA-Seq-based drug repurposing targeting idiopathic pulmonary fibrosis (IPF)

2022-09-17

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease, which affects around three million people worldwide and is characterized by impaired regeneration from recurrent injury to the alveolar epithelium resulting in progressive lung scarring. In this work, we target a cell transition in the differentiation of AT2 cells into mature AT1 cells which is inhibited in IPF and contributes to the regeneration of th...

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Literature Corpus work: 20955b8e-eced-5a1a-8b37-c32416de99e9
DOI: 10.1101/2022.09.17.508360

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