Article
The Role of Propionate-Induced Rearrangement of Membrane Proteins in the Formation of the Virulent Phenotype of Crohn's Disease-Associated Adherent-Invasive Escherichia coli.
International journal of molecular sciences - 20 Sept 2024
Pobeguts Olga V, Galyamina Maria A, Mikhalchik Elena V, Kovalchuk Sergey I, Smirnov Igor P, Lee Alena V, Filatova Lyubov Yu, Sikamov Kirill V, Panasenko Oleg M, Gorbachev Alexey Yu
Abstract excerpt
Adhesive-invasive E. coli has been suggested to be associated with the development of Crohn's disease (CD). It is assumed that they can provoke the onset of the inflammatory process as a result of the invasion of intestinal epithelial cells and then, due to survival inside macrophages and dendritic cells, stimulate chronic inflammation. In previous reports, we have shown that passage of the CD isolate ZvL2 on...
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