Article

Atlas of Cynomolgus Macaque Hematopoiesis

2024-04-26

Abstract excerpt

<h4>Summary</h4> Self-renewal and differentiation are inherent properties of hematopoietic stem cells (HSCs) that are necessary to support hematopoiesis; however, the underlying mechanisms, especially in human, remain unclear. Here, using the cynomolgus macaque as a surrogate model, we develop a new gating strategy to isolate with high purity transplantable cynomolgus HSCs and generated a single-cell transcriptom...

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Literature Corpus work: 20879c3c-7eb6-5da3-9194-3e41c8139c05
DOI: 10.1101/2024.04.22.590220

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