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Article

A distinct hematopoietic stem cell population for rapid multilineage engraftment in nonhuman primates.

Science translational medicine - 1 Nov 2017

Radtke Stefan, Adair Jennifer E, Giese Morgan A, Chan Yan-Yi, Norgaard Zachary K, Enstrom Mark, Haworth Kevin G, Schefter Lauren E, Kiem Hans-Peter

Abstract excerpt

Hematopoietic reconstitution after bone marrow transplantation is thought to be driven by committed multipotent progenitor cells followed by long-term engrafting hematopoietic stem cells (HSCs). We observed a population of early-engrafting cells displaying HSC-like behavior, which persisted long-term in vivo in an autologous myeloablative transplant model in nonhuman primates. To identify this population, we...

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Identifiers

PMID: 29093179
DOI: 10.1126/scitranslmed.aan1145
PMCID: PMC6467214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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