Article

Spontaneous Facet Joint Osteoarthritis in NFAT1-Mutant Mice

2022-02-15

Abstract excerpt

Background: Facet joint (FJ) osteoarthritis (FJOA) is a widely prevalent spinal disorder but its pathogenesis remains unclear, largely due to the difficulties in conducting longitudinal human studies and lack of spontaneous-FJOA animal models for mechanistic investigations. This study aimed to investigate whether spontaneous FJOA occurs in mice bearing mutant NFAT1 (nuclear factor of activated T cells 1) transcrip...

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Literature Corpus work: 2016e17b-b529-565a-88c6-3d0a9b2a81a0
DOI: 10.2106/jbjs.21.00960

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