Article

Systematic Review of Cerebral Phenotypes Associated with Monogenic Cerebral Small Vessel Disease

2021-11-14

Abstract excerpt

<h4>Background</h4> Cerebral small vessel disease (cSVD) is an important cause of stroke and vascular dementia. Most cases are multifactorial, but an emerging minority have a monogenic cause. While NOTCH3 is the best-known gene, several others have been reported. We aimed to summarise the cerebral phenotypes associated with these more recent cSVD genes. <h4>Methods</h4> We performed a systematic review (PROSPERO:...

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Literature Corpus work: 6a9e993c-d3c3-547c-a829-e0590e5df814
DOI: 10.1101/2021.11.12.21266276

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