Article

Race- and sex-specific disease trajectory in individuals with rare variants in seven cerebrovascular small vessel disease genes: a genotype-first population study

2022-08-12

Abstract excerpt

<h4>Background</h4> This study is aimed to explore the risk for a lifetime or early onset of cardiovascular diseases and diseases within or beyond the circulatory system observed in rare variant(RV) carriers of seven well-characterized monogenic cerebral small vessel disease (CSVD) risk genes ( COL4A1, COL4A2, NOTCH3, HTRA1, TREX1, CTC1 , and GLA ) using a genotype-first approach within a hospital system populatio...

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Literature Corpus work: 72c684a2-3372-54c1-8786-6fe0356b4f90
DOI: 10.1101/2022.08.11.22278284

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