Article

Whole Exome Sequencing of Suspected Monogenic Cerebral Small Vessel Disease Patients reveals Novel Gene Associations

2026-02-16

Abstract excerpt

Cerebral small vessel diseases (CSVDs) are a group of disorders affecting the small arteries, veins, and capillaries supplying the white matter and deep grey matter structures. They are the most common form of cerebrovascular disease, accounting for almost half of vascular dementia cases worldwide and approximately 20% of stroke incidence. Whilst genetic testing is a routine diagnostic tool for monogenic CSVDs, le...

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Literature Corpus work: 22bfc430-a8f9-5c3f-8b3a-05c4ab80851f
DOI: 10.64898/2026.02.08.26345868

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