Article

Sex-specific genome-wide association study in glioma identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21

2017-12-18

Abstract excerpt

Incidence of glioma is approximately 50% higher in males. Previous analyses have examined exposures related to sex hormones in women as potential protective factors for these tumors, with inconsistent results. Previous glioma genome-wide association studies (GWAS) have not stratified by sex. Potential sex-specific genetic effects were assessed in autosomal SNPs and sex chromosome variants for all glioma, GBM and n...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1f8321ee-1acb-5bfe-8fc1-c76a10c6e875
DOI: 10.1101/229112

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Sex-specific genome-wide association study in glioma identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21DOI 10.1101/229112Read

Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21.Semantic proximity Read

Sex differences in health and disease: A review of biological sex differences relevant to cancer with a spotlight on gliomaSemantic proximity Read

Region-Based Analyses of Existing Genome-Wide Association Studies Identifies Novel Potential Genetic Susceptibility Regions for Glioma.Semantic proximity Read

Australian genome-wide association study confirms higher female risk for adult glioma associated with variants in the region of CCDC26.Semantic proximity Read

Sex-specific gene and pathway modeling of inherited glioma risk.Semantic proximity Read

Impact of Sex Hormones on Glioblastoma: Sex-Related Differences and Neuroradiological InsightsSemantic proximity Read

Sex-Specific Differences in Glioblastoma.Semantic proximity Read

Genome-Wide Sex and Gender Differences in CancerSemantic proximity Read

Joint associations between genetic variants and reproductive factors in glioma risk among women.Semantic proximity Read

Sex-specific differences in DNA methylation defining prognostically relevant subgroups in glioblastomaSemantic proximity Read

Unveiling the role of SRY in male-biased cancers: Insights into the molecular basis of sex disparities in high-grade glioma and melanomaSemantic proximity Read

Genome-Wide Association Studies in Glioma.Semantic proximity Read