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Article

Australian genome-wide association study confirms higher female risk for adult glioma associated with variants in the region of CCDC26.

Neuro-oncology - 6 Jul 2023

Alpen Karen, Vajdic Claire M, MacInnis Robert J, Milne Roger L, Koh Eng-Siew, Hovey Elizabeth, Harrup Rosemary, Bruinsma Fiona, Nguyen Tuong L, Li Shuai, Joseph David, Benke Geza, Dugué Pierre-Antoine, Southey Melissa C, Giles Graham G, Rosenthal Mark, Drummond Katharine J, Nowak Anna K, Hopper John L, Kapuscinski Miroslaw, Makalic Enes

Abstract excerpt

BACKGROUND: Glioma accounts for approximately 80% of malignant adult brain cancer and its most common subtype, glioblastoma, has one of the lowest 5-year cancer survivals. Fifty risk-associated variants within 34 glioma genetic risk regions have been found by genome-wide association studies (GWAS) with a sex difference reported for 8q24.21 region. We conducted an Australian GWAS by glioma subtype and sex....

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Identifiers

PMID: 36541697
DOI: 10.1093/neuonc/noac279
PMCID: PMC10326491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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