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Impact of Sex Hormones on Glioblastoma: Sex-Related Differences and Neuroradiological Insights

21 Nov 2024

Abstract excerpt

Glioblastoma (GBM) displays significant gender disparities, being 1.6 times more prevalent in men, with a median survival time of 15.0 months for males compared to 25.5 months for females. These differences may be linked to gonadal steroid hormones, particularly testosterone, which interacts with the androgen receptor (AR) to promote tumor proliferation. Conversely, estrogen (E2), progesterone (P4), and P4...

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PMID: 39768232
DOI: 10.3390/life14121523

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