Article
Region-Based Analyses of Existing Genome-Wide Association Studies Identifies Novel Potential Genetic Susceptibility Regions for Glioma.
Cancer research communications - 1 Nov 2024
Alpen Karen, Maclnnis Robert J, Vajdic Claire M, Lai John, Dowty James G, Koh Eng-Siew, Hovey Elizabeth, Harrup Rosemary, Nguyen Tuong L, Li Shuai, Joseph David, Benke Geza, Dugué Pierre-Antoine, Southey Melissa C, Giles Graham G, Nowak Anna K, Drummond Katharine J, Schmidt Daniel F, Hopper John L, Kapuscinski Miroslaw K, Makalic Enes
Abstract excerpt
SIGNIFICANCE: Further investigation of the potential susceptibility regions identified in our study may lead to a better understanding of glioma genetic risk and the underlying biological etiology of glioma. Our study suggests sex may play a role in genetic susceptibility and highlights the importance of sex-specific analysis in future glioma research.
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