Article

Human<i>in vivo</i>footprints from blood plasma samples for improved diagnostics in septic patients

2025-01-29

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> Liquid biopsy based on cell-free DNA (cfDNA) is an established approach in clinical diagnostics. In recent years, a fraction of cfDNA comprising short fragments has been discovered, that is enriched at gene promoters and binding sites of DNA-binding proteins. However, the diagnostic potential of such short double-stranded cell-free DNA (footprint DNA) remains to be fully explor...

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Literature Corpus work: 1f7ad60e-c5cc-5d80-b0b2-259221ac6db0
DOI: 10.1101/2025.01.29.25320179

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