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Cell-Free DNA as Biomarker for Sepsis by Integration of Microbial and Host Information

30 Jun 2022

Abstract excerpt

BACKGROUND: Cell-free DNA (cfDNA) is emerging as a biomarker for sepsis. Previous studies have been focused mainly on identifying blood infections or simply quantifying cfDNA. We propose that by characterizing multifaceted unexplored components, cfDNA could be more informative for assessing this complex syndrome. METHODS: We explored multiple aspects of cfDNA in septic and nonseptic intensive care unit (ICU)...

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PMID: 35771673
DOI: 10.1093/clinchem/hvac097

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