Article

Brain biomechanics governs mitotic fidelity of embryonic neural progenitors

2025-08-01

Abstract excerpt

Accurate chromosome segregation is essential to maintain genetic stability and prevent the onset of diseases such as developmental disorders, infertility, and cancer. While many intrinsic factors and processes involved in mitosis have been extensively characterized, less is known about how extrinsic factors and tissue properties contribute to mitotic fidelity. In this study, using both in vivo and ex vivo system...

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Literature Corpus work: 1f222434-50a2-5e08-bec7-e6aa226021d3
DOI: 10.1101/2025.07.31.667957

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