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<i>TAOK3</i> inhibition constrains invasion, potentiates paclitaxel, and reprograms the tumor microenvironment toward anti-tumor immunity in cervical cancer

2026-07-06

Abstract excerpt

TAOK3 is a lesser-studied MAPK family serine/threonine kinase our group has shown to be targeted by HPV integration, suggesting a potential role in driving invasive cervical cancer (ICC). Here, we profiled TAOK3 expression in patient tumors, metastases, and cervical cancer models and localized TAOK3 within a tumor epithelial subpopulation by integrating two single-cell RNA-seq datasets. Functional consequences o...

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Literature Corpus work
1f089375-33ec-5d15-ad7a-ceec5cf3634e
DOI
10.64898/2026.07.04.736128
Open publication

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<i>TAOK3</i> inhibition constrains invasion, potentiates paclitaxel, and reprograms the tumor microenvironment toward anti-tumor immunity in cervical cancerDOI 10.64898/2026.07.04.736128
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