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The Hippo pathway transcription factors YAP and TAZ play HPV-type dependent roles in cervical cancer

10 Jul 2024

Abstract excerpt

Human papillomaviruses (HPVs) cause most cervical cancers and an increasing number of anogenital and oral carcinomas, with most cases caused by HPV16 or HPV18. HPV hijacks host signalling pathways to promote carcinogenesis. Understanding these interactions could permit identification of much-needed therapeutics for HPV-driven malignancies. The Hippo signalling pathway is important in HPV+ cancers, with the...

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PMID: 38987584
DOI: 10.1038/s41467-024-49965-9

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