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Multi-omics characterization of cellular state diversity and bidirectional tumor-stroma/immune interactions in cervical squamous cell carcinoma

2023-04-14

Abstract excerpt

<title>Abstract</title> <p>Cervical cancer ranks as the fourth leading cause of cancer-related deaths among women, with low response rates to immune-checkpoint blockade (ICB). Here we conducted a multidimensional analysis encompassing single-cell RNA-seq (scRNA-seq), spatial transcriptomics, and spatial proteomics, combined with genetic and pharmacological perturbations to systematically develop a high-resolution...

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Literature Corpus work
77e968d9-a389-598e-8398-1639d4fc6ad9
DOI
10.21203/rs.3.rs-2726910/v1
Open publication

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