Article

A single measurement of fecal hemoglobin concentration outperforms polygenic risk score in colorectal cancer risk assessment

2022-07-22

Abstract excerpt

<h4>PURPOSE</h4> Polygenic risk scores (PRS) have been proposed and are increasingly used for risk assessment in colorectal cancer (CRC) screening. Fecal immunochemical tests (FITs) are widely recommended and used as dichotomous tests for annual or biennial CRC screening, ignoring the quantitative information on fecal hemoglobin concentration above or below the positivity threshold. <h4>MATERIALS AND METHODS</h4>...

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Literature Corpus work: fa8176b7-8306-5efc-99a5-dab3d1857ecc
DOI: 10.1101/2022.07.22.22277924

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