Article

A Statistical Framework for Evolutionary Analysis of Recurrent Somatic Mutations in Cancers

2020-04-13

Abstract excerpt

Current cancer genomics databases have accumulated millions of somatic mutations that remain to be further explored, faciltating enormous high throuput analyses to explore the underlying mechanisms that may contribute to malignant initiation or progression. In the context of over-dominant passenger mutations (unrelated to cancers), the challenge is to identify somatic mutations that are cancer-driving. Under the n...

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Literature Corpus work: 1ead074c-801c-588d-9d5b-0348bdaee147
DOI: 10.1101/2020.04.10.036095

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