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Coexistence of two divergent TprA/PhrA cell-cell communication systems in <i>Streptococcus mitis</i> coordinate bacteriocin production, competence, oxidative stress responses, and interspecies competition with <i>S. pneumoniae</i>

2025-12-10

Abstract excerpt

<h4>ABSTRACT</h4> Cell-cell communication (CCC) systems are key regulators of bacterial behaviors and adaptation. The human upper respiratory tract is co-colonized by commensal and pathogenic streptococci, but how CCC systems mediate their interactions remains unclear. Here, we investigated the TprA/PhrA quorum-sensing system, composed of the transcription factor TprA and its cognate signaling peptide PhrA, acros...

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Literature Corpus work
b7c314a3-dd32-5ada-a73d-a9921d934ff9
DOI
10.64898/2025.12.10.693483
Open publication

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Coexistence of two divergent TprA/PhrA cell-cell communication systems in <i>Streptococcus mitis</i> coordinate bacteriocin production, competence, oxidative stress responses, and interspecies competition with <i>S. pneumoniae</i>DOI 10.64898/2025.12.10.693483
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