Article

Cross-phosphorylation of RR06 by the non-cognate kinase VncS activates the adhesin CbpA in <i>Streptococcus pneumoniae</i>

2026-07-16

Abstract excerpt

<h4>ABSTRACT</h4> Streptococcus pneumoniae establishes asymptomatic nasopharyngeal colonization before progressing to invasive disease, a process that requires precise spatiotemporal regulation of surface adhesins. Using a barcoded capsule-switch mutant library and randomly barcoded transposon sequencing (RB-TnSeq), we identified determinants of pneumococcal adhesion to the human alveolar epithelial cell line A54...

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Literature Corpus work: 08e863a5-ba36-5b26-b8c9-126cf803737b
DOI: 10.64898/2026.07.15.738638

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