Article

Meta-analysis of exhausted CD8+ T cells from <i>Homo sapiens</i> and <i>Mus musculus</i> provides robust targets for immunotherapy

2021-07-05

Abstract excerpt

T cell exhaustion is a state of T cell dysfunction during chronic infection and cancer. Antibody-targeting immune checkpoint inhibitors to reverse T cell exhaustion is a promising approach for cancer immunotherapy. However, the therapeutic efficacy of known immune checkpoint inhibitors remains low. To expand the potential effective targets to reverse T cell exhaustion, a meta-analysis was performed to integrate se...

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Literature Corpus work: 1e66c4c0-d60f-51a2-996a-869c70711049
DOI: 10.1101/2021.07.05.451111

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