Article

Sperm acrosome overgrowth and infertility in mice lacking chromosome 18 pachytene piRNA

2020-09-29

Abstract excerpt

piRNAs are germline-specific, small non-coding RNAs required to maintain genome integrity and preserve RNA homeostasis during male gametogenesis. In murine adult testes, the highest levels of piRNAs are present in the pachytene stage of meiosis, but their mode of action and function remains incompletely understood. We previously reported that BTBD18 binds to 50 pachytene piRNA-producing loci. Here we show that spe...

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Literature Corpus work: 1e120cd9-4197-5660-b865-fa58da4b84d8
DOI: 10.1101/2020.09.29.318584

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