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Circulating Myeloid-Derived Suppressor Cell load and disease severity are associated to an enhanced oligodendroglial production in a murine model of multiple sclerosis

2024-07-22

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Multiple sclerosis (MS) is a chronic, inflammatory and demyelinating disease of the central nervous system (CNS) that is highly heterogeneous in terms of disease severity and tissue damage extent. Improving myelin restoration is essential to prevent neurodegeneration and the associated disability in MS patients. However, remyelinating therapies are failing in clinical trials...

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Literature Corpus work
1dff3c88-f5a0-57c2-8323-8c4387041e18
DOI
10.1101/2024.07.18.604171
Open publication

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Circulating Myeloid-Derived Suppressor Cell load and disease severity are associated to an enhanced oligodendroglial production in a murine model of multiple sclerosisDOI 10.1101/2024.07.18.604171
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