Article

Augmentation of a neuroprotective myeloid state by hematopoietic cell transplantation

2023-03-12

Abstract excerpt

<h4>Summary</h4> Multiple sclerosis (MS) is an autoimmune disease associated with inflammatory demyelination in the central nervous system (CNS). Autologous hematopoietic cell transplantation (HCT) is under investigation as a promising therapy for treatment-refractory MS. Here we identify a reactive myeloid state in chronic experimental autoimmune encephalitis (EAE) mice and MS patients that is surprisingly assoc...

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Literature Corpus work: 81f3b38c-8959-5637-962c-faf252b4987f
DOI: 10.1101/2023.03.10.532123

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